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Organic–Inorganic Composite Nanorods as an Excellent Mimicking Peroxidases for Colorimetric Detection and Evaluation of Antioxidant
journal contribution
posted on 2020-03-19, 18:40 authored by Hao Liu, YanLei He, Ning Li, Zhenxue Liu, Xianxi Zhang, Xiao Zhang, Qingyun LiuN,N′-Dicarboxy methyl perylene
diimide-coated CeO2 nanorods (PDI/CeO2 NR) were
synthesized via an ultrasonic-assisted
method. PDI/CeO2 exhibits the superb mimic peroxidase functions
confirmed by the catalyzed oxidation of TMB by hydrogen peroxide in
less than 60 s along with color transformation from colorless to blue.
The catalytic mechanism was confirmed to be an electronic transfer
mechanism by fluorescence experiment. Thus, a visual colorimetric
sensor was constructed for hydrogen peroxide detection with a low
detection limit (LOD = 2.23 μM). Comparing the inhibition effects
of l-cysteine (Cys), ascorbic acid (AA) and glutathione (GSH)
on the catalytic oxidation of TMB, it can be found that they possessed
different types of inhibition on the oxidation of TMB by H2O2 using PDI/CeO2, and AA has better antioxidant
effect, followed by Cys and GSH. On the basis of the excellent antioxidant
effect of AA, a low-cost colorimetric sensor was also used to detect
AA, and a lower LOD value (0.68 μM) was obtained in the linear
range of 5.0–30 μM.