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Occurrence of Pharmaceuticals and Personal Care Products in German Fish Tissue: A National Study
journal contribution
posted on 2012-08-21, 00:00 authored by Bikram Subedi, Bowen Du, C. Kevin Chambliss, Jan Koschorreck, Heinz Rüdel, Markus Quack, Bryan W. Brooks, Sascha UsenkoGerman Environment Specimen Bank (GESB) fish tissue samples,
collected
from 14 different GESB locations, were analyzed for 15 pharmaceuticals,
2 pharmaceutical metabolites, and 12 personal care products. Only
2 pharmaceuticals, diphenhydramine and desmethylsertraline, were measured
above MDL. Diphenhydramine (0.04–0.07 ng g–1 ww) and desmethylsertraline (1.65–3.28 ng g–1 ww) were measured at 4 and 2 locations, respectively. The maximum
concentrations of galaxolide (HHCB) (447 ng g–1 ww)
and tonalide (AHTN) (15 ng g–1 ww) were measured
at the Rehlingen sampling site in the Saar River. A significant decrease
in HHCB and AHTN fish tissue concentrations was observed from 1995
to 2008 at select GESB sampling sites (r2 = 0.69–0.89 for galaxolide and 0.89–0.97 for tonalide
with p < 0.003). Galaxolide and tonalide fish
tissue concentrations in Germany were ∼19× and ∼28×
lower, respectively, as compared to fish tissue concentrations measured
in a United States nationwide PPCP study conducted in 2006. Proximity
of the sampling locations to the upstream wastewater treatment plant
discharging point and mean annual flow at the sampling location were
found to significantly predict galaxolide and tonalide fish tissue
concentrations (HHCB: r2 = 0.79, p = 0.021 and AHTN: r2 = 0.81, p = 0.037) in Germany.
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German Fish Tissuer 2Rehlingen sampling sitetonalide fish tissue concentrationswwHHCBAHTN fish tissue concentrationspharmaceuticalMDLlocationdesmethylsertralinefish tissue concentrationsgalaxolideGESB sampling sitesPersonal Care ProductsNational StudyGerman Environment Specimen Bankfish tissue sampleswastewater treatment plantPPCP
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