ol200808q_si_001.pdf (2.57 MB)
Nucleophilic Deoxyfluorination of Catechols
journal contribution
posted on 2011-05-20, 00:00 authored by Hiroyuki Nemoto, Tsuyoshi Nishiyama, Shuji AkaiNucleophilic deoxyfluorinaiton of one of the two hydroxyl groups of catechols has been developed via the Umpolung concept. This method was successively applied to naturally occurring catechols, such as catechins and dopamine, to produce novel fluorinated analogues.