Novel Sulfinyl Imine Ligands for Asymmetric Catalysis

2003-01-21T00:00:00Z (GMT) by Laurie B. Schenkel Jonathan A. Ellman
A novel class of P,N-sulfinyl imine ligands has been prepared that incorporates chirality solely at sulfur. The Pd complex of ligand 14 catalyzes the allylic alkylation reaction with high enantioselectivity (94%), and the first crystal structure of a Pd-bound sulfinyl imine provides insight into binding mode and origins of stereoselectivity.