Neurosporaside, a Tetraglycosylated Sphingolipid from <i>Neurospora crassa</i>

The new tetraglycosylceramide neurosporaside (<b>1a</b>) has been isolated from the fungus <i>Neurospora crassa</i>. Neurosporaside is a tetraglycosylated glycosphingolipid characterized by a sugar chain unprecedented among natural glycoconjugates. The structure of neurosporaside was elucidated by extensive spectroscopic analysis and microscale degradation analysis, which allowed full structure elucidation using less than 1 mg of compound.