Neighboring π‑Amide Participation in Thioether Oxidation: Conformational Control
2016-07-11T20:48:34Z (GMT)
by
The electrochemical oxidation of
thioethers is shown to be facilitated
by neighboring amide participation. 1H NMR spectroscopic
analysis in acetonitrile solution of two conformationally constrained
compounds with such facilitation shows that two-electron participation
by the amide π2 orbital can occur to stabilize the
developing sulfur radical cation.
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