ac501586d_si_002.pdf (214.53 kB)
Near Infrared (NIR) Strong Field Ionization and Imaging of C60 Sputtered Molecules: Overcoming Matrix Effects and Improving Sensitivity
journal contribution
posted on 2014-09-02, 00:00 authored by Andrew Kucher, Lauren M. Jackson, Jordan O. Lerach, A. N. Bloom, N. J. Popczun, Andreas Wucher, Nicholas WinogradStrong field ionization (SFI) was
applied for the secondary neutral
mass spectrometry (SNMS) of patterned rubrene films, mouse brain sections,
and Botryococcus braunii algal cell
colonies. Molecular ions of rubrene, cholesterol, C31 diene/triene,
and three wax monoesters were detected, representing some of the largest
organic molecules ever ionized intact by a laser post-ionization experiment.
In rubrene, the SFI SNMS molecular ion signal was ∼4 times
higher than in the corresponding secondary-ion mass spectroscopy (SIMS)
analysis. In the biological samples, the achieved signal improvements
varied among molecules and sampling locations, with SFI SNMS, in some
cases, revealing analytes made completely undetectable by the influence
of matrix effects in SIMS.