NHC−Iron-Catalyzed Aerobic Oxidative Aromatic Esterification of Aldehydes using Boronic Acids

Rosa, João N.; Reddy, R. Sudarshan; Candeias, Nuno R.; M. S. D. Cal, Pedro; M. P. Gois, Pedro

doi:10.1021/ol100302e.s001

ol100302e_si_001.pdf (760.01 kB)

NHC−Iron-Catalyzed Aerobic Oxidative Aromatic Esterification of Aldehydes using Boronic Acids

journal contribution

posted on 2010-06-18, 00:00 authored by João N. Rosa, R. Sudarshan Reddy, Nuno R. Candeias, Pedro M. S. D. Cal, Pedro M. P. Gois

NHC−iron complexes prepared in situ very efficiently afforded benzoates via the aerobic oxidative aromatic esterification of aldehydes with boronic acids. This method uses equimolar amounts of both the aldehyde and the boronic acid allowing the preparation of benzoates in yields up to 97%.