am6b05515_si_001.pdf (695.14 kB)
Molecularly Imprinted Polymer (MIP) Film with Improved Surface Area Developed by Using Metal–Organic Framework (MOF) for Sensitive Lipocalin (NGAL) Determination
journal contribution
posted on 2016-07-25, 00:00 authored by Zofia Iskierko, Piyush
Sindhu Sharma, Daniel Prochowicz, Krzysztof Fronc, Francis D’Souza, Diana Toczydłowska, Filip Stefaniak, Krzysztof NoworytaElectropolymerizable functional and
cross-linking monomers were used to prepare conducting molecularly
imprinted polymer film with improved surface area with the help of
a sacrificial metal–organic framework (MOF). Subsequent dissolution
of the MOF layer resulted in a surface developed MIP film. This surface
enlargement increased the analyte accessibility to imprinted molecular
cavities. Application of the porous MIP film as a recognition unit
of an extended-gate field effect transistor (EG-FET) chemosensor effectively
enhanced analytical current signals of determination of recombinant
human neutrophil gelatinase-associated lipocalin (NGAL)