cs0c01074_si_001.pdf (2.82 MB)
Mechanistic Understanding of the Heterogeneous, Rhodium-Cyclic (Alkyl)(Amino)Carbene-Catalyzed (Fluoro-)Arene Hydrogenation
journal contribution
posted on 2020-05-21, 16:03 authored by Daniel Moock, Mario P. Wiesenfeldt, Matthias Freitag, Satoshi Muratsugu, Satoru Ikemoto, Robert Knitsch, Jacob Schneidewind, Wolfgang Baumann, Andreas H. Schäfer, Alexander Timmer, Mizuki Tada, Michael Ryan Hansen, Frank GloriusRecently, chemoselective
methods for the hydrogenation of fluorinated,
silylated, and borylated arenes have been developed providing direct
access to previously unattainable, valuable products. Herein, a comprehensive
study on the employed rhodium-cyclic (alkyl)(amino)carbene (CAAC)
catalyst precursor is disclosed. Mechanistic experiments, kinetic
studies, and surface-spectroscopic methods revealed supported rhodium(0)
nanoparticles (NP) as the active catalytic species. Further studies
suggest that CAAC-derived modifiers play a key role in determining
the chemoselectivity of the hydrogenation of fluorinated arenes, thus
offering an avenue for further tuning of the catalytic properties.