Lactonecembranoids from Croton laevigatus
2010-04-23T00:00:00Z (GMT) by
Six new cembranoids, laevigatlactones A−F (1−6), and the known compound neocrotocembraneic acid (7) were isolated from leaves of Croton laevigatus. Their structures were elucidated on the basis of spectroscopic analysis, and that of 1 was confirmed by X-ray crystallography. Compound 2 exhibited modest cytotoxicity against HeLa cells, with an IC50 value of 38.4 μM.
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