Iridium Complex-Catalyzed Highly Selective Cross [2 + 2 + 2] Cycloaddition of Two Different Monoynes: 2:1 Coupling versus 1:2 Coupling
2003-09-06T00:00:00Z (GMT) by
Highly selective cross [2 + 2 + 2] cycloaddition of two different monoynes is achieved by using a catalytic amount of [Ir(cod)Cl]2 and ligand. The ligand had a considerable effect on the reaction. When 1,2-bis(diphenylphosphino)ethane was used, two molecules of dimethyl acetylenedicarboxylate (DMAD) reacted with one molecule of a monoyne to give the 2:1 coupling product. When 1,2-bis(dipentafluorophenylphosphino)ethane was used instead of dppe, one molecule of DMAD reacted with two molecules of a monoyne to give the 1:2 coupling product.