Intramolecular Iron-Mediated Diene/Olefin Cyclocoupling: Formation of Carbon Spirocycles
2004-07-22T00:00:00Z (GMT) by
A short and convenient diastereoselective synthesis of all-carbon spirocylic molecules was developed. A straightforward protocol that involves rearrangement of the diene−Fe(CO)3 complex followed by cyclization delivers the desired product. The reaction substrates were easily prepared by reaction of an appropriate nucleophile and a cyclohexadienyl-Fe(CO)3 cation.