In Situ Oxidation−Imine Formation−Reduction Routes from Alcohols to Amines

2001-05-05T00:00:00Z (GMT) by Leonie Blackburn Richard J. K. Taylor
Manganese dioxide is employed as an in situ oxidant for the one-pot conversion of alcohols into imines. In combination with polymer-supported cyanoborohydride (PSCBH), a one-pot oxidation−imine formation−reduction sequence is reported. This procedure enables alcohols to be converted directly into both secondary and tertiary amines.