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In Situ Measurement of 3D Crystal Size Distribution by Double-View Image Analysis with Case Study on l‑Glutamic Acid Crystallization
journal contribution
posted on 2020-02-25, 12:34 authored by Yan Huo, Tao Liu, Yixuan Yang, Cai Y. Ma, Xue Z. Wang, Xiongwei NiAn
in situ measurement method is proposed for monitoring three-dimensional
(3D) crystal size distribution (CSD) during a crystallization process,
based on a binocular microvision system. The stereo particle shape
is reconstructed from double-view images captured by two microscopic
cameras fixed at different angles outside the crystallizer. To overcome
the influence from solution turbulence and uneven illumination background
involved with in situ imaging, a microscopic double-view image analysis
method is established to identify the key corners of each particle
shape in the captured images, including corner detection and corner
matching. Two fast algorithms are therefore given for online detection
of two typical crystal morphologies of prismatic and needle-like shapes,
such as α- and β-forms of l-glutamic acid (LGA)
crystals, respectively. On the basis of the identified key corners
for different particle shapes, a 3D geometry model is established
to approximately reconstruct the 3D shape for each imaged particle,
such that 3D sizes of each particle could be quantitatively estimated,
along with the particle volume. Experiments on the LGA cooling crystallization
are performed to demonstrate the effectiveness of the proposed method.
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Keywords
particle volumel-glutamic acidparticle shapes3 D shapestereo particle shapeLGA cooling crystallizationDouble-View Image AnalysisSitu MeasurementCSDβ- formscrystal morphologiesmeasurement methodparticle shape3 D sizescrystal size distributioncorner detection3 D Crystal Size Distributionbinocular microvision systemcrystallization processdouble-view imagesdouble-view image analysis methodillumination backgroundCase Study3 D geometry modelsolution turbulence
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