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Imazamox: A Quest for Polymorphic Modifications of a Chiral and Racemic Herbicide

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posted on 2014-03-05, 00:00 authored by Dario Braga, Laura Chelazzi, Fabrizia Grepioni, Saverio Nanna, Katia Rubini, Marco Curzi, Stefano Giaffreda, Heidi E. Saxell, Matthias Bratz, Tiziana Chiodo
The structure–property relationships of new polymorphs of the chiral herbicide imazamox were investigated by X-ray diffraction, hot stage microscopy (HSM), and differential scanning calorimetry (DSC). Four different polymorphs of imazamox­(R) were found. The relationship between different crystal forms, relative thermal stability, and possible conversions pathways was explored. Racemic imazamox, for which no polymorphic modifications could be observed, was also characterized in the solid state.

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