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Focused Fluorescent Probe Library for Metal Cations and Biological Anions

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journal contribution
posted on 2013-09-09, 00:00 authored by Hyun-Woo Rhee, Sang Wook Lee, Jun-Seok Lee, Young-Tae Chang, Jong-In Hong
A focused fluorescent probe library for metal cations was developed by combining metal chelators and picolinium/quinolinium moieties as combinatorial blocks connected through a styryl group. Furthermore, metal complexes derived from metal chelators having high binding affinities for metal cations were used to construct a focused probe library for phosphorylated biomolecules. More than 250 fluorescent probes were screened for identifying an ultraselective probe for dTTP.

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