Fluoro- and Chloroferrocene: From 2- to 3‑Substituted
Derivatives

Tazi, Mehdi; Hedidi, Madani; Erb, William; Halauko, Yury S.; Ivashkevich, Oleg A.; Matulis, Vadim E.; Roisnel, Thierry; Dorcet, Vincent; Bentabed-Ababsa, Ghenia; Mongin, Florence

doi:10.1021/acs.organomet.8b00384.s001

om8b00384_si_001.pdf (6.85 MB)

Fluoro- and Chloroferrocene: From 2- to 3‑Substituted Derivatives

journal contribution

posted on 2018-07-10, 14:03 authored by Mehdi Tazi, Madani Hedidi, William Erb, Yury S. Halauko, Oleg A. Ivashkevich, Vadim E. Matulis, Thierry Roisnel, Vincent Dorcet, Ghenia Bentabed-Ababsa, Florence Mongin

The ferrocene halogen “dance” has been deemed hardly controllable. Here, we describe the first efficient examples of this reaction. Conversion of 1-fluoro-2-iodo (or 1-chloro-2-iodo) to 1-fluoro-3-iodo (or 1-chloro-3-iodo) ferrocenes was ensured by suitably protecting the free 5-position.