om301219t_si_001.cif (41.24 kB)
Facile and Regioselective C–H Bond Activation of Aromatic Substrates by an Fe(II) Complex Involving a Spin-Forbidden Pathway
dataset
posted on 2013-03-25, 00:00 authored by Steven
E. Kalman, Alban Petit, T. Brent Gunnoe, Daniel H. Ess, Thomas R. Cundari, Michal SabatThe
Fe(II) complex Cp*Fe(CO)(NCMe)Ph (Cp* = η5-pentamethylcyclopentadienyl)
is shown to mediate facile and highly
regioselective C–H activation of aromatic substrates including
benzene, furan, thiophene, thiazole, and 2-methylfuran. Experimental
and computational evidence suggest a mechanism for C–H activation
that involves NCMe dissociation, multiple spin intersystem crossings,
C–H bond coordination, and C–H bond cleavage by a σ-bond
metathesis reaction.