ol5b01590_si_001.pdf (8.07 MB)
Facile Synthesis of Carbazoles via a Tandem Iodocyclization with 1,2‑Alkyl Migration and Aromatization
journal contribution
posted on 2015-06-19, 00:00 authored by Jia Wang, Hai-Tao Zhu, Yi-Feng Qiu, Yuan Niu, Si Chen, Ying-Xiu Li, Xue-Yuan Liu, Yong-Min LiangA strategy
for the synthesis of iodocarbazoles through a tandem
iodocyclization with migration and aromatization is presented. This
sequential cascade process is concisely conducted at room temperature
and in a short time. Moreover, the obtained halides can be further
applied to palladium-catalyzed coupling reactions, which act as the
important intermediates for building other valuable compounds.