Expedient Five-Step Synthesis of SIB-1508Y from Natural Nicotine
2006-10-27T00:00:00Z (GMT)
by
Altinicline (SIB-1508Y), an anti-Parkinson's agent, was
prepared in five steps from natural nicotine in 32% overall
yield via a regioselective substitution of the pyridine ring of
(S)-nicotine.
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CC BY-NC 4.0