ol2009297_si_001.pdf (6.38 MB)
Enol Silyl Ethers via Copper(II)-Catalyzed C–O Bond Formation
journal contribution
posted on 2011-05-20, 00:00 authored by Daniel G. Chan, David J. Winternheimer, Craig A. MerlicCopper(II) acetate catalyzes the coupling of pinacol vinylboronates with silanols producing enol silyl ethers. This represents a novel enol silyl ether synthesis via formation of the C–O bond instead of the conventional Si–O bond. This also constitutes the first transition-metal-catalyzed oxidative cross-coupling with silanols.