Enantioselective α-Amination of 1,3-Dicarbonyl Compounds Using Squaramide Derivatives as Hydrogen Bonding Catalysts
journal contributionposted on 07.05.2010 by Hideyuki Konishi, Tin Yiu Lam, Jeremiah P. Malerich, Viresh H. Rawal
Any type of content formally published in an academic journal, usually following a peer-review process.
Catalytic enantioselective α-hydrazination of 1,3-dicarbonyl compounds with azodicarboxylates was investigated in the presence of our newly developed hydrogen bonding catalyst, squaramide 3j. High yields and high enantioselectivities were achieved with low catalyst loading under mild conditions.