Efficient Preparation of Nitrosoarenes for the Synthesis of Azobenzenes<sup>†</sup>
2005-03-18T00:00:00Z (GMT) by
Reaction conditions are described for the oxidation of anilines furnishing nitrosoarenes and the synthesis of unsymmetrically substituted azobenzenes. In a comparative study, the catalytic oxidation of methyl 4-aminobenzoate by hydrogen peroxide was investigated, and SeO<sub>2</sub> proved to be superior or equal to methyl trioxorhenium (MTO) and Na<sub>2</sub>WO<sub>4</sub>, respectively. Nevertheless, the application of the inexpensive, environmentally friendly, Oxone in a biphasic system proved to be more efficient, and a variety of useful nitrosoarenes for the synthesis of azo compounds were prepared in high yield and purity on a large scale.
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