ol200067e_si_006.pdf (3.9 MB)
Diversity-Oriented Approach to Pyrrole-Imidazole Alkaloid Frameworks
journal contribution
posted on 2011-03-18, 00:00 authored by Manojkumar R. Bhandari, Muhammed Yousufuddin, Carl J. LovelyAn exploration of imidazolylpropargyl amides as linchpin synthons for the construction of a diverse array of heterocyclic frameworks, many of which are related to those found in the oroidin derived alkaloids, is described. One such intermediate has been used in a formal total synthesis of cyclooroidin.