Diastereoselective Synthesis of Polysubstituted Spirocyclopenta[<i>c</i>]furans by Gold-Catalyzed Cascade Reaction

With the synergistic activation of alkynyl alcohols and alkynyl enones by a single gold catalyst, diverse multisubstituted spirocyclopenta­[<i>c</i>]­furans were synthesized in good to excellent yields under mild conditions. Three rings were constructed efficiently in one pot from easily available acyclic starting materials.