ol8b03880_si_001.pdf (9.41 MB)
Diastereoselective Synthesis of Polysubstituted Spirocyclopenta[c]furans by Gold-Catalyzed Cascade Reaction
journal contribution
posted on 2019-01-11, 20:15 authored by Jialin Qi, Qi Teng, Nuligonda Thirupathi, Chen-Ho Tung, Zhenghu XuWith the synergistic activation of
alkynyl alcohols and alkynyl
enones by a single gold catalyst, diverse multisubstituted spirocyclopenta[c]furans were synthesized in good to excellent yields under
mild conditions. Three rings were constructed efficiently in one pot
from easily available acyclic starting materials.