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Development of a QuEChERS-Based Method for Determination of Carcinogenic 2‑Nitrofluorene and 1‑Nitropyrene in Rice Grains and Vegetables: A Comparative Study with Benzo[a]pyrene
journal contribution
posted on 2017-02-20, 00:00 authored by Kailin Deng, Wan ChanNitrated polycyclic
aromatic hydrocarbons (nitro-PAHs) are ubiquitous environmental pollutants
attracting increasing attention because of their potent mutagenicity
to humans. Previous studies of nitro-PAHs focused on investigating
their formation mechanisms and detecting them in atmospheric environment;
however, few studies have reported their occurrence in food samples,
and regulations on nitro-PAHs are still lacking. We report in this
study the development and application of a quick, easy, cheap, effective,
rugged, and safe (QuEChERS) method for determination of nitro-PAHs
in rice and vegetable samples. Analysis of the collected samples by
the validated method revealed 1-nitropyrene and 2-nitrofluorene were
widespread food contaminants. A comparative study with benzo[a]pyrene, the commonly used marker for PAH exposure, showed
that carcinogenic nitro-PAHs existed in rice and vegetables at similar
concentrations. Dietary exposure risk, which was estimated based on
the surveillance data, suggested 3.28–5.03 ng/kg/day of nitro-PAHs
exposure for Hong Kong citizens from rice grains and vegetables.