jp9b09741_si_001.pdf (3.07 MB)
DNA-Hairpin-Templated Silver Nanoclusters: A Study on Stem Sequence
journal contribution
posted on 2020-02-25, 13:03 authored by Yahui Guo, Fumiao Shen, Yuliang Cheng, Hang Yu, Yunfei Xie, Weirong Yao, Renjun Pei, He Qian, Hung-Wing LiDNA hairpins are
widely used to synthesize silver nanoclusters
(AgNCs) with excellent optical properties due to their specific secondary
structure. Hairpin-AgNCs have been popularly employed for sensoring
applications, while no systematic study has been done about the effect
of stem sequence on the fluorescence property of hairpin-AgNCs. In
this presented work, the synthesizing conditions of hairpin-AgNCs
were fully examined first. Then, the effect of percentage content
and distribution of GC base pairs as well as stem length on the fluorescence
property of hairpin-AgNCs were studied. Intriguing phenomena were
observed and basic conclusions were drawn, which would be helpful
to understand the hairpin-AgNCs comprehensively and instructional
for the applications using hairpin-AgNC probes.