CuBr-Catalyzed Efficient Alkynylation of sp3 C−H Bonds Adjacent to a Nitrogen Atom

2004-09-29T00:00:00Z (GMT) by Zhiping Li Chao-Jun Li
A simple and effective catalytic method to construct propargylamine was developed by using copper bromide and tert-BuOOH via a combination of sp3 C−H bond and sp C−H bond activations followed by C−C bond formation.