cg401891f_si_001.pdf (3.59 MB)
Crystal Landscape of Primary Aromatic Thioamides
journal contribution
posted on 2014-06-04, 00:00 authored by Kevin
S. Eccles, Robin E. Morrison, Anita R. Maguire, Simon E. LawrenceThe
crystal landscape of a series of primary aromatic thioamides
is described, displaying similar characteristic intermolecular hydrogen-bonding
interactions in the solid state to those observed in their widely
studied amide analogues, including R22(8) dimers and C(4) chains. In a number of
cases, high Z′ values were observed in the
structures. On the basis of the observed solid-state features, the
thioamide functional group, which is a strong hydrogen-bond donor
and moderate acceptor, offers considerable potential as a key moiety
for crystal engineering.