Crystal Landscape of Primary Aromatic Thioamides

The crystal landscape of a series of primary aromatic thioamides is described, displaying similar characteristic intermolecular hydrogen-bonding interactions in the solid state to those observed in their widely studied amide analogues, including R<sub>2</sub><sup>2</sup>(8) dimers and C(4) chains. In a number of cases, high <i>Z</i>′ values were observed in the structures. On the basis of the observed solid-state features, the thioamide functional group, which is a strong hydrogen-bond donor and moderate acceptor, offers considerable potential as a key moiety for crystal engineering.