Copper-Catalyzed Allylation of Carbonyl
Derivatives Using Allyl(2-pyridyl)silanes

Kamei, Toshiyuki; Fujita, Kazuyoshi; Itami, Kenichiro; Yoshida, Jun-ichi

doi:10.1021/ol051925s.s001

ol051925s_si_001.pdf (490.14 kB)

Copper-Catalyzed Allylation of Carbonyl Derivatives Using Allyl(2-pyridyl)silanes

journal contribution

posted on 2005-10-13, 00:00 authored by Toshiyuki Kamei, Kazuyoshi Fujita, Kenichiro Itami, Jun-ichi Yoshida

We have developed an efficient copper-catalyzed allylation of carbonyl derivatives using allyl(2-pyridyl)silanes, in which the strong directing effect of the 2-pyridyl group was observed. A useful synthesis and allylation of substituted allyl(2-pyridyl)silanes is also described.