Convenient Synthesis of Triphenylphosphanylidene Spiro[cyclopentane-1,3′-indolines] and Spiro[cyclopentene-1,3′-indolines] via Three-Component Reactions
2014-05-16T00:00:00Z (GMT) by
Three-component reactions of triphenylphosphine, but-2-ynedioate, and isatylidene malononitrile (ethyl cyanoacetate) in dimethoxyethane resulted in triphenylphosphanylidene spiro[cyclopentane-1,3′-indolines] in satisfactory yields. Furthermore, similar three-component reactions of triphenylphosphine, hex-2-en-4-ynedioate, and isatylidene malononitrile (ethyl cyanoacetate) afforded functionalized spiro[cyclopentene-1,3′-indolines] in good yields.
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