Convenient Synthesis of Triphenylphosphanylidene Spiro[cyclopentane-1,3′-indolines] and Spiro[cyclopent[2]ene-1,3′-indolines] via Three-Component Reactions

2014-05-16T00:00:00Z (GMT) by Ying Han Yin-Jian Sheng Chao-Guo Yan
Three-component reactions of triphenyl­phosphine, but-2-ynedioate, and isatylidene malononitrile (ethyl cyanoacetate) in dimethoxyethane resulted in triphenyl­phos­phanyli­dene spiro­[cyclo­pentane-1,3′-indolines] in satisfactory yields. Furthermore, similar three-component reactions of triphenylphosphine, hex-2-en-4-ynedioate, and isatylidene malononitrile (ethyl cyanoacetate) afforded functionalized spiro­[cyclo­pent[2]­ene-1,3′-indolines] in good yields.