ol6b03267_si_001.pdf (6.47 MB)
Construction of Polycyclic γ‑Lactams and Related Heterocycles via Electron Catalysis
journal contribution
posted on 2016-11-29, 14:20 authored by Jun Xuan, Constantin G. Daniliuc, Armido StuderCascade radical cyclization of 1,6-enynes
for the construction
of biologically important polycyclic γ-lactams and related heterocycles
is reported. In these radical cascade processes, three new C–C
bonds are formed and transition metals are not required to run these
sequences. The mild reaction conditions, broad substrate scope, and
the importance of the heterocyclic products render the approach valuable.