jo800906p_si_001.pdf (1.62 MB)
Concise Total Synthesis of (+)-Crocacin C
journal contribution
posted on 2008-08-15, 00:00 authored by Gopal Sirasani, Tapas Paul, Rodrigo B. AndradeThe cytotoxic natural product (+)-crocacin C (1) has been synthesized in 10 linear steps from commercially available Evans’ chiral propionimide in 5% overall yield (8 steps from Evans’ chiral dipropionate synthon). No protecting groups were utilized.