ol702265h_si_003.pdf (193.75 kB)
Cobalt-Catalyzed Intramolecular C−H Amination with Arylsulfonyl Azides
journal contribution
posted on 2007-11-08, 00:00 authored by Joshua V. Ruppel, Rajesh M. Kamble, X. Peter ZhangCobalt complexes of porphyrins are effective catalysts for intramolecular C−H amination with arylsulfonyl azides. The cobalt-catalyzed process
can proceed efficiently under mild and neutral conditions in low catalyst loading without the need of other reagents or additives, generating
nitrogen gas as the only byproduct. The catalytic system can be applied to primary, secondary, and tertiary C−H bonds and is suitable for a
broad range of arylsulfonyl azides, leading to high-yielding syntheses of various benzosultams.