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Chromium-Catalyzed Arylmagnesiation of Alkynes

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journal contribution
posted on 2007-04-12, 00:00 authored by Kei Murakami, Hirohisa Ohmiya, Hideki Yorimitsu, Koichiro Oshima
Arylmagnesiation of unfunctionalized alkynes in the presence of catalytic amounts of chromium(II) chloride and pivalic acid proceeds with high stereoselectivity. The alkenylmagnesium intermediate reacts with various electrophiles to afford the corresponding tetrasubstituted olefins in good yields.

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