ol0703938_si_001.pdf (497.93 kB)
Chromium-Catalyzed Arylmagnesiation of Alkynes
journal contribution
posted on 2007-04-12, 00:00 authored by Kei Murakami, Hirohisa Ohmiya, Hideki Yorimitsu, Koichiro OshimaArylmagnesiation of unfunctionalized alkynes in the presence of catalytic amounts of chromium(II) chloride and pivalic acid proceeds with
high stereoselectivity. The alkenylmagnesium intermediate reacts with various electrophiles to afford the corresponding tetrasubstituted olefins
in good yields.