Chiral Phosphine Oxide–Sc(OTf)<sub>3</sub> Complex Catalyzed Enantioselective Bromoaminocyclization of 2‑Benzofuranylmethyl <i>N</i>‑Tosylcarbamates. Approach to a Novel Class of Optically Active Spiro Compounds

2015-12-04T00:00:00Z (GMT) by Zequan Li Yian Shi
An efficient enantioselective bromoaminocyclization of 2-benzofuranylmethyl <i>N</i>-tosylcarbamates catalyzed by a chiral phosphine oxide–Sc­(OTf)<sub>3</sub> complex is described. A wide variety of optically active spiro benzofuran oxazolidinones can be obtained with high enantioselectivities.