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Chemoselective Cyclizations of Divinyl Ketones to Cyclohexenones Mediated by Lewis Acid and Base

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posted on 2004-09-16, 00:00 authored by Nabi A. Magomedov, Piero L. Ruggiero, Yuchen Tang
Chemoselective cyclizations of divinyl ketones to cyclohexenones mediated by a sterically demanding Lewis acid and an amine base have been accomplished under mild reaction conditions. The extension of this methodology to the synthesis of eight-membered rings is also demonstrated.

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