Cation Exchange Strategy for the Encapsulation of
a Photoactive CO-Releasing Organometallic Molecule into Anionic Porous
Frameworks

Carmona, Francisco J.; Rojas, Sara; Sánchez, Purificación; Jeremias, Hélia; Marques, Ana R.; Romão, Carlos
C.; Choquesillo-Lazarte, Duane; A. R. Navarro, Jorge; Maldonado, Carmen R.; Barea, Elisa

doi:10.1021/acs.inorgchem.6b00674.s001

ic6b00674_si_001.pdf (1.04 MB)

Cation Exchange Strategy for the Encapsulation of a Photoactive CO-Releasing Organometallic Molecule into Anionic Porous Frameworks

journal contribution

posted on 2016-06-03, 11:37 authored by Francisco J. Carmona, Sara Rojas, Purificación Sánchez, Hélia Jeremias, Ana R. Marques, Carlos C. Romão, Duane Choquesillo-Lazarte, Jorge A. R. Navarro, Carmen R. Maldonado, Elisa Barea

The encapsulation of the photoactive, nontoxic, water-soluble, and air-stable cationic CORM [Mn(tacn)(CO)₃]Br (tacn = 1,4,7-triazacyclononane) in different inorganic porous matrixes, namely, the metalorganic framework bio-MOF-1, (NH₂(CH₃)₂)₂[Zn₈(adeninate)₄(BPDC)₆]·8DMF·11H₂O (BPDC = 4,4′-biphenyldicarboxylate), and the functionalized mesoporous silicas MCM-41-SO₃H and SBA-15-SO₃H, is achieved by a cation exchange strategy. The CO release from these loaded materials, under simulated physiological conditions, is triggered by visible light. The results show that the silica matrixes, which are unaltered under physiological conditions, slow the kinetics of CO release, allowing a more controlled CO supply. In contrast, bio-MOF-1 instability leads to the complete leaching of the CORM. Nevertheless, the degradation of the MOF matrix gives rise to an enhanced CO release rate, which is related to the presence of free adenine in the solution.