ol502285s_si_001.pdf (1.43 MB)
Carboxylic Acid-Catalyzed Highly Efficient and Selective Hydroboration of Alkynes with Pinacolborane
journal contribution
posted on 2014-09-05, 00:00 authored by Hon Eong Ho, Naoki Asao, Yoshinori Yamamoto, Tienan JinWe
have demonstrated for the first time that carboxylic acids are
able to catalyze the direct hydroboration of various terminal and
internal alkynes with pinacolborane without using any metal catalysts.
This unprecedented catalytic hydroboration exhibits a broad functional
groups compatibility, giving the corresponding alkenyl diboronates
and monoboronates in good to high yields with exclusive regio- and
stereoselectivities.