ja512728f_si_009.cif (5.94 kB)
C–H Activation/Functionalization Catalyzed by Simple, Well-Defined Low-Valent Cobalt Complexes
dataset
posted on 2015-02-25, 00:00 authored by Brendan
J. Fallon, Etienne Derat, Muriel Amatore, Corinne Aubert, Fabrice Chemla, Franck Ferreira, Alejandro Perez-Luna, Marc PetitA facile
C–H activation and functionalization of aromatic
imines is presented using low-valent cobalt catalysts. Using Co(PMe3)4 as catalyst we have developed an efficient and
simple protocol for the C–H/hydroarylation of alkynes with
an anti selectivity. Deuterium-labeling experiments,
DFT calculations coupled with the use of a well-defined catalyst have
for the first time shed light on the elusive black box of cobalt catalyzed
C–H functionalization.
