ol0158213_si_001.pdf (76.03 kB)
BINOL−Salen Metal Catalysts Incorporating a Bifunctional Design
journal contribution
posted on 2001-05-03, 00:00 authored by Erin F. DiMauro, Marisa C. KozlowskiSalen metal complexes incorporating two chiral BINOL moieties have been synthesized and characterized crystallographically. The corresponding
bisnaphthoxide complexes have been found to catalyze the asymmetric addition of benzyl malonate to cyclohexenone in up to 90% ee. With
these modular catalysts, the Lewis acid and Bronsted base portions can be independently altered.