ol0708166_si_001.pdf (171.48 kB)
Asymmetric Synthesis of syn-α-Substituted β-Amino Ketones by Using Sulfinimines and Prochiral Weinreb Amide Enolates
journal contribution
posted on 2007-06-07, 00:00 authored by Franklin A. Davis, Minsoo Songsyn-α-Substituted β-amino Weinreb amides are new chiral building blocks for asymmetric synthesis of syn-α-substituted β-amino acids,
aldehydes, and ketones and are prepared by addition of prochiral lithium enolates of Weinreb amides to sulfinimines (N-sulfinyl imines).