ol8013864_si_001.pdf (725.63 kB)
Asymmetric Synthesis of (+)-Isofebrifugine and (−)-Sedacryptine from a Common Chiral Nonracemic Building Block
journal contribution
posted on 2008-09-04, 00:00 authored by Andrew G. H. Wee, Gao-Jun FanThe stereoselective syntheses of 2-substituted and 2,6-disubstituted 3-hydroxypiperidine alkaloids, (+)-isofebrifugine and (−)-sedacryptine, from a common, functionalized nonracemic bicyclic building block are achieved, demonstrating the flexibilty of the approach.