ab9b01695_si_001.pdf (891.63 kB)
Antibacterial Properties of Bilayer Biomimetic Nano-ZnO for Dental Implants
journal contribution
posted on 2020-03-11, 20:17 authored by Xiaheng Wang, Houyou Fan, Feng Zhang, Siyu Zhao, Yuxiao Liu, Yingying Xu, Runfa Wu, Dongfang Li, Yang Yang, Lan Liao, Hongshui Zhu, Xiaolei WangDental
implant surgery has a relatively high incidence of peri-implantitis.
In this research, ZnO nanorods and ZnO nanospheres were synthesized
by a hydrothermal method. ZnO nanorods first covered the surface of
Ti or Ti–Zr, and ZnO nanospheres were then modified as the
outermost layer. By these means a dual antibacterial effect could
be realized by the rapid release of ZnO nanospheres and the sustained
release of ZnO nanorods. Subsequent studies implied that this ZnO
nanorods–nanospheres hierarchical structure (NRS) could be
stably loaded on the surface of roughened Ti and Ti–Zr slices.
The modified materials not only showed excellent antibacterial activities
against both Escherichia coli and Staphylococcus aureus but also showed low cellular
cytotoxicity. This ZnO NRS structure is thus expected to be used as
a general antimicrobial coating on the surface of Ti (Ti–Zr)
in dental implant surgery.