An Efficient Approach to 3,4-Disubstituted Pyridin-2-ones. Formal
Synthesis of Mappicine Ketone

Lin, Ching H.; Tsai, Min R.; Wang, Yung S.; Chang, Nein C.

doi:10.1021/jo034042s.s001

jo034042s_si_001.pdf (121.96 kB)

An Efficient Approach to 3,4-Disubstituted Pyridin-2-ones. Formal Synthesis of Mappicine Ketone

journal contribution

posted on 2003-06-17, 00:00 authored by Ching H. Lin, Min R. Tsai, Yung S. Wang, Nein C. Chang

Treatment of 3,4-dihydro-3-tosylpyridin-2-one 5 with sodium hydride and then alkyl halides gave various 3,4-disubstituted pyridin-2-ones 6. Formal synthesis of mappicine ketone (1) was also reported.

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Keywords

Formal synthesis alkyl halides mappicine ketone sodium hydride Pyridin Synthesi Disubstituted pyridin Efficient Approach disubstituted Mappicine Ketone Treatment dihydro

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