Alkali Metal-Hydroxide-Catalyzed C(<i>sp</i>)–H Bond silylation
2016-12-27T00:00:00Z (GMT) by
Disclosed is a mild, scalable, and chemoselective catalytic cross-dehydrogenative C–H bond functionalization protocol for the construction of C(<i>sp</i>)–Si bonds in a single step. The scope of the alkyne and hydrosilane partners is substantial, providing an entry point into various organosilane building blocks and additionally enabling the discovery of a number of novel synthetic strategies. Remarkably, the optimal catalysts are NaOH and KOH.