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A cis Amide Bond Surrogate Incorporating 1,2,4-Triazole

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journal contribution
posted on 17.04.2002 by Yukio Hitotsuyanagi, Shuichi Motegi, Haruhiko Fukaya, Koichi Takeya
A novel cis amide bond surrogate incorporating 1,2,4-triazole was designed and synthesized by the reaction of a thionotripeptide, formic hydrazide, and mercury(II) acetate. This method of surrogate formation was also applicable to a cyclic thionopeptide.