A Short and Efficient Synthesis of Crocetin-dimethylester and Crocetindial
2003-10-23T00:00:00Z (GMT) by
In this paper we describe an efficient six-step synthesis of crocetin-dimethylester that could be further reduced to a “four-step” synthesis through the use of in situ procedures. The simplicity of the whole process, the ready availability of starting materials, and the high overall yield render this strategy a very attractive synthesis of this very important compound, which is the key intermediate for the synthesis of several carotenoids and other polyene natural products.
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