jo3010183_si_001.pdf (2.17 MB)
A Photochemical Route to 2‑Substituted Benzo[b]furans
journal contribution
posted on 2012-08-03, 00:00 authored by Stefano Protti, Maurizio Fagnoni, Angelo Albini2-Substituted benzo[b]furans were synthesized
by a one-step metal-free photochemical reaction between 2-chlorophenol
derivatives and terminal alkynes by tandem formation of an aryl-C
and a C–O bond via an aryl cation intermediate. The mild conditions
and the application to chlorophenols rather of the more expensive
bromo or iodo analogues makes this procedure environmentally convenient.